"A deepening understanding of the biology of the 7TM family of receptors … is likely to pay rich dividends at several levels. First it will provide fundamental insights into the structure and function of what is arguably the most pervasive, ubiquitous and versatile type of signalling molecule known. Additionally, such information will probably lead directly to the development of many new, more selective therapeutic agents, further enhancing the role of 7TM receptors in drug development."
— Robert Lefkowitz